Minority Health Archive

Genetic and Environmental Contributions to Racial Disparities in Preterm Birth

Dolan, Siobhan M. (2010) Genetic and Environmental Contributions to Racial Disparities in Preterm Birth. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine, 77 (2). pp. 160-165. ISSN 00272507

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Abstract

The preterm birth rate exceeds 12% in the United States, and preterm birth continues to be a clinical and public health challenge globally. Even though preterm birth is a major contributor to infant mortality and lifelong morbidity, there are few effective strategies to predict preterm birth and few clinical interventions to prevent it. Genomic research approaches that identify risk factors at the intersection of genetics and the environment will likely provide insights. Both genetic and environmental factors are known to contribute to the racial disparity seen in preterm birth. Through the identification of relevant gene-environment interactions that contribute to preterm birth and may underlie the racial disparity in preterm birth, research that will translate to clinical practice and ultimately prevent a number of preterm births is possible. Mt Sinai J Med 77:160–165, 2010. © 2010 Mount Sinai School of Medicine


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Item Type: Article
Additional Information: This article is available at the publisher’s Web site. Access to the full text is subject to the publisher’s access restrictions.
Uncontrolled Keywords: common complex disorder; genetics; genomics; preterm birth
Subjects: Health > Disparities
Health > Prenatal & Pediatric Health
Research > Genetics and Race
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Depositing User: Users 141 not found.
Date Deposited: 26 Jul 2011 13:22
Last Modified: 26 Jul 2011 13:22
Link to this item (URI): http://health-equity.pitt.edu/id/eprint/2870

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